Pathology of SDD-treated Rodents in ACC-TS and NTP Studies

This report includes the reviews of histologically-prepared duodenal specimens from studies in which F344/N rats and B6C3F1 mice were treated with varying doses of sodium dichromate dihydrate (SDD). The results of the pathology peer slide review of non-neoplastic findings in the duodenum of mice and rats treated with SDD in ACC-TS and NTP studies are found in the following tables:

• ACC-TS female mice vs ACC-TS female rats at 90 days (Tables 2 and 3)
• ACC-TS female mice vs NTP female and male mice at 90 days (Tables 2, 5, and 6)
• ACC-TS female rats vs NTP female and male rats at 90 days (Tables 3, 7, and 8)
• NTP female mice vs NTP male mice vs NTP female rats vs NTP male rats at 90 days (Tables 5, 6, 7, and 8)
• ACC-TS female rats at 8 days vs ACC-TS female rats at 90 days (Tables 3 and 4)
• NTP female and male mice at 2 years vs 90 days (Tables 5, 6, 9, and 10)
• NTP female and male rats at 2 years vs 90 days (Tables 7, 8, 11, and 12)