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Pathology of SDD-treated Rodents in ACC-TS and NTP Studies

This report includes the reviews of histologically-prepared duodenal specimens from studies in which F344/N rats and B6C3F1 mice were treated with varying doses of sodium dichromate dihydrate (SDD).

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Rat Glutathione Data Day 8

Used in: Figure 9 from Thompson et al. (2012), Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action Figure 2 from Thompson et al. … Continue reading

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Rat Glutathione Data Day 91

Figures 6, 7 and Table 6 from Thompson et al. (2012), Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action

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Total Cr in Scraped Duodenal Epithelium – Rat

Used in: Figure 4 from Thompson et al. (2012), Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action

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Total Chromium in Rat Tissues

Used in: Figures 4 and 5 from Thompson et al. (2012), Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action; Table 2 from Kirman et … Continue reading

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Mouse Glutathione Data Day 91

Used in: Figure 2 and Table 4 from Thompson et al. (2011), Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium;  Figure 6 from Kopec et al. (2012), Genome-wide gene expression effects in B6C3F1 … Continue reading

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Total Chromium in Mouse Tissues

Used in: Figure 3 from Thompson et al. (2013), Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans; Figure 9 from Kopec et al. (2012), Genome-wide gene expression effects in … Continue reading

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SRI – Rat 90 Day Study

Used in: Figures S1, S2, S3 and Tables 2, 3, 4, S2 from Thompson et al. (2012), Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of … Continue reading

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SRI – Mouse 90 Day Study

Used in: Figures 1, 3, S2, S3 and  Tables 2, S2, S3 from Thompson et al. (2011), Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium;  Table 2 from Thompson et al. (2012) Comparison of … Continue reading

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