Cr(VI) MOA Study Awards

The Cr(VI) Mode of Action (MOA) Research Team has been granted several awards by the Society of Toxicology (SOT) for their novel, cutting-edge scientific research. These include:

  • SOT 2013 Risk Assessment Speciality Section – Best Published Paper Advancing the Science of Risk Assessment – four of ten papers recognized by SOT
  1.  Kirman, CR, Hays, SM, Aylward, LL, Suh, M, Harris, MA, Thompson, CM, Haws, LC, Proctor, DM. Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium. Chem Biol Interact. 200(1): 45-64.
  2. Kopec, A.K., C.M. Thompson, S. Kim, A.L. Forgacs, T.R. Zacharewski. 2012. Comparative Toxicogenomic Analysis of Oral Cr(VI) Exposure Effects in Rat and Mouse Small Intestinal Epithelium. Toxicol Appl Pharmacol. 262(2): 124-38.
  3. Kopec, A.K., Kim, S., Forgacs, A.L., Zacharewski, T.R., Proctor, D.M., Harris, M.A., Haws, L.C, Thompson, C.M.2012. Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water. Toxicology and Applied Pharmacology. 259(1):13-26.
  4. Thompson, C.M., D.M. Proctor, M. Suh, L.C. Haws, C.D. Hebert, J.F. Mann, H.G. Shertzer, J.G. Hixon and M.A. Harris. 2012. Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action. Toxicol Sci. 125(1):79-90.
  1. Thompson CM, Haws LC, Harris MA, Gatto NM, Proctor DM. Application of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium. Toxicol Sci. 2011 Jan;119(1):20–40.2012.