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NTP 2-year Study

Used in: Figures 4, 6, and Tables 1, 2 from Thompson et al. (2011), Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium; Figures 1, 4, 5, … Continue reading

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Undifferentiated Caco-2 Data

Used in: Figures 1,3, S1 and Table 1 from Thompson et al. (2012), Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis; Figure 8 from Thompson et al. (2013) Assessment of the mode of action underlying development of rodent small intestinal tumors following … Continue reading

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Total Chromium in Mouse Tissues

Used in: Figure 3 from Thompson et al. (2013), Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans; Figure 9 from Kopec et al. (2012), Genome-wide gene expression effects in … Continue reading

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A549 Micronucleus Data

Used in: Table 3 from Thompson et al. (2012), Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis;  Figure 7 from Thompson et al. (2013), Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure … Continue reading

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CHO-K1 Micronucleus Data

Used in: Table 2 from Thompson et al. (2012) Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis; Figure 7 from Thompson et al. (2013) Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to … Continue reading

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ATF6 Localization in Caco-2 Data

Used in: Figure 6 from Thompson et al. (2012) Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis

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Caco-2 Nuclear Area Data

Used in: Figure 2 from Thompson et al. (2012) Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis

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Differentiated Caco-2 Data

Used in: Figures 1,3, 5, S1 and Table 1 from Thompson et al. (2012), Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis;  Figure 8 from Thompson et al. (2013), Assessment of the mode of action underlying development of rodent small intestinal tumors … Continue reading

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K-Ras codon 12 GGT to GAT mutant fraction (MF) in mouse duodenal tissue using ACB-PCR

Used in: Table 3 from O’Brien et al . (2013) Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water

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Histopathologic Evaluation of Mouse Duodenum

Used in: Figure 8 from Kopec et al. (2012) Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water; Figure 2 and  Tables 1 &2 of O’Brien et al . (2013) Assessment … Continue reading

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