Blog Archives

Genomics analysis files used in Kopec et al. 2012 publications

Posted on March 8, 2018 by Seneca Harvey

A zipped folder containing the analysis code and results from the Kopec 2012 publications can be obtained by following the “download” link to the right and downloading from a secure Dropbox location. The zipped folder includes:

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Pathology of SDD-treated Rodents in ACC-TS and NTP Studies

Posted on July 6, 2015 by Seneca Harvey

This report includes the reviews of histologically-prepared duodenal specimens from studies in which F344/N rats and B6C3F1 mice were treated with varying doses of sodium dichromate dihydrate (SDD).

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Iron Homeostasis Study Data

Posted on June 2, 2015 by Seneca Harvey

Used in: Figures 1-4, Figure S1, and Table 2 from Suh et al. (2014), High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice.

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7-day Micronucleus Study

Posted on June 2, 2015 by Seneca Harvey

Used in: Figure 1F and Table 1 from Thompson et al. (2015), Duodenal crypt health following exposure to Cr(VI):  Micronucleus scoring γ-H2AX immunostaining, and synchrotron X-ray fluorescence microscopy.

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Synchrotron Analysis of Rodent Duodenum

Posted on June 2, 2015 by Seneca Harvey

Used in: Figures 2E, 2F, 3D, S5 and Tables 1 and S4 in Thompson et al. (2015), Synchrotron-Based Imaging of Chromium and c-H2AX Immunostaining in the Duodenum Following Repeated Exposure to Cr(VI) in Drinking Water.

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Cr(VI) Big Blue® Rat Study Data

Posted on June 1, 2015 by Seneca Harvey

Used in: Figure 1, Table 1 and Table 3 from Thompson et al. (2015), Assessment of the Mutagenic Potential of Cr(VI) in the Oral Mucosa of Big Blue Transgenic F344 Rats.

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QRT-PCR Genomics Data

Posted on April 28, 2014 by Daniele Wikoff

Used in: Figures 3 and 6 from Kopec et al. (2012), Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water; Figure 3, 9, and S5  from Kopec et al. (2012), … Continue reading →

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Rodent PBPK Models

Posted on March 21, 2014 by Daniele Wikoff

Used in: Figure 1 from Proctor et al. (2012), Hexavalent chromium reduction kinetics in rodent stomach contents 

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Human PBPK Models

Posted on March 21, 2014 by Daniele Wikoff

Used in: Figure 1 from Proctor et al. (2012), Hexavalent chromium reduction kinetics in rodent stomach contents   

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Total Cr in Scraped Duodenal Epithelium – Mouse

Posted on March 20, 2014 by Daniele Wikoff

Used in: Figure 4 from Thompson et al. (2011), Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium

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