Blog Archives
NTP 2-year Study
Used in: Figures 4, 6, and Tables 1, 2 from Thompson et al. (2011), Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium; Figures 1, 4, 5, … Continue reading
Undifferentiated Caco-2 Data
Used in: Figures 1,3, S1 and Table 1 from Thompson et al. (2012), Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis; Figure 8 from Thompson et al. (2013) Assessment of the mode of action underlying development of rodent small intestinal tumors following … Continue reading
Total Chromium in Mouse Tissues
Used in: Figure 3 from Thompson et al. (2013), Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans; Figure 9 from Kopec et al. (2012), Genome-wide gene expression effects in … Continue reading
A549 Micronucleus Data
Used in: Table 3 from Thompson et al. (2012), Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis; Figure 7 from Thompson et al. (2013), Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure … Continue reading
CHO-K1 Micronucleus Data
Used in: Table 2 from Thompson et al. (2012) Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis; Figure 7 from Thompson et al. (2013) Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to … Continue reading
ATF6 Localization in Caco-2 Data
Used in: Figure 6 from Thompson et al. (2012) Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis
Caco-2 Nuclear Area Data
Used in: Figure 2 from Thompson et al. (2012) Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis
Differentiated Caco-2 Data
Used in: Figures 1,3, 5, S1 and Table 1 from Thompson et al. (2012), Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis; Figure 8 from Thompson et al. (2013), Assessment of the mode of action underlying development of rodent small intestinal tumors … Continue reading
K-Ras codon 12 GGT to GAT mutant fraction (MF) in mouse duodenal tissue using ACB-PCR
Used in: Table 3 from O’Brien et al . (2013) Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water
Histopathologic Evaluation of Mouse Duodenum
Used in: Figure 8 from Kopec et al. (2012) Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water; Figure 2 and Tables 1 &2 of O’Brien et al . (2013) Assessment … Continue reading